Events relating to the medici

Hippocrates, on the Greek island of Kos, founds an influential school of medicine

The Alexandrian school of medicine develops an alarming form of clinical anatomy – human vivisection

The practice of acupuncture is described in Nei Qing, a Chinese medical text

The Roman surgeon Cornelius Celsus describes in De Medicina how to cut stones from a patient's bladder

The Persian scholar Avicenna, author of encyclopedic works on philosophy and medicine, spends the last part of his life in Isfahan

Cosimo de' Medici, arrested by a rival faction, escapes with his life thanks to bribes and well-placed friends

Sandro Botticelli is established as one of the leading painters of Florence, working in particular for the Medici

Tommaso Portinari, the Medici agent in Bruges, commissions an altarpiece from Hugo van der Goes for his family church in Florence

A plot by the Pazzi family, with papal connivance, results in the murder of Guiliano de' Medici during high mass in Florence's cathedral

Botticelli paints the Birth of Venus and Spring for the villa of a Medici cousin of Lorenzo the Magnificent

Leonardo da Vinci begins an unprecedented series of detailed anatomical drawings, based on corpses dissected in Rome

Savonarola, the new prior of San Marco, is a stern critic of both the pope in Rome and the Medici in Florence

Soft-paste porcelain, in imitation of true porcelain from China, is successfully created for the Medici in Florence

Samuel Pepys has a two-ounce stone cut from his bladder, in an operation carried out at home in the presence of his family

The first recorded attempt at blood transfusion, at the Royal Society in London, proves that the idea is feasible

Captain Cook publishes his discovery of a preventive cure against scurvy, in the form of a regular ration of lemon juice

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