Events relating to europe

Raphael begins work on the frescoes in the pope's apartment in the Vatican, known as the Stanze ('Rooms')

On the death of his father, and as the result of the death of his elder brother Arthur, Henry VIII becomes king of England

Erasmus and Thomas More take the northern Renaissance in the direction of Christian humanism

Giorgione and Titian introduce the richness of colour which characterizes the high Renaissance style in Venice

The startling colour contrasts in Michelangelo's Sistine ceiling anticipate one of the main characteristics of Italian mannerism

The Portuguese take control of Malacca, in the Malay peninsula, as a base for trade further east

The death of Ferdinand II results in Spain becoming part of the Habsburg empire, under the rule of Charles V (as Charles I of Spain)

Catherine of Aragon gives birth to a daughter, Mary, who becomes the only one of her six children to live beyond infancy

The original ghetto is established as a district to which the Jews of Venice are confined

Ariosto, in Orlando Furioso, tells of Roland's madness when he is abandoned by the pagan princess Angelica

Erasmus publishes an influential edition of the New Testament in its original Greek

From Bosnia to Egypt and Arabia, the Ottoman Turks now rule the largest Muslim empire since the early caliphate - and will frequently use the title of caliph to assert their authority within Sunni Islam

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