Events relating to religion
Torquemada persuades Ferdinand and Isabella to expel from Spain all Jews (about 160,000) who will not convert to Christianity
Bayazid II, the Turkish sultan, makes a special point of welcoming in Istanbul the Jews expelled from Spain
Rodrigo Borgia, elected pope as Alexander VI, already has four illegitimate children and possibly sires three more while pope
Savonarola, in the carnival before Lent, urges the people of Florence to throw playing cards and lewd images on a great bonfire of vanities
The Florentine mob, weary of puritanism, attacks the convent of San Marco and drags Savonarola away to be hanged and burnt
Nanak, the first of the Sikh gurus, takes to the road as a wandering teacher
In Cuzco's great temple, the sacrifices are usually of llamas, occasionally of humans
The original ghetto is established as a district to which the Jews of Venice are confined
Erasmus publishes an influential edition of the New Testament in its original Greek
The local sale of indulgences by Johann Tetzel outrages a friar teaching in Wittenberg, Martin Luther

Martin Luther nails his 95 Theses to the door of the castle church in Wittenberg
Philipp Melanchthon joins the Wittenberg university to teach Greek and inspires Luther to translate the New Testament
Europe's new printing presses make possible the first pamphlet war, spreading instant arguments for and against the Reformation
Luther's writings are burnt in Rome by order of the pope
Pope Leo X excommunicates Martin Luther after he has refused to recant
Luther travels to the German city of Worms to present his case to an imperial diet
Luther bears witness to a Protestant conscience, stating at Worms: 'Here I stand, I can not do otherwise.'
Ignatius of Loyola, recovering from a wound received as a soldier at Pamplona, is inspired by reading the lives of the saints
Outlawed by the Edict of Worms, Luther lives secretly in the Wartburg as Junker Georg
Huldreich Zwingli eats sausage in Lent in Zurich, launching the Swiss Reformation
Hans Sachs, popular poet and master singer, describes Luther as the Wittenberg nightingale
William Tyndale studies in the university at Wittenberg and plans to translate the Bible into English
Luther, a former friar, marries Catherine von Bora, a former nun who has just emerged from her convent
Conrad Grebel baptises an adult, causing outrage in Protestant Zurich
Thomas Müntzer leads the rebels in the Peasant War, to the profound displeasure of Luther