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| 1849 |
| | | Vancouver Island is given the status of a British crown colony, to be followed by British Columbia in 1858 | |
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| 1849 |
| | | Dante Gabriel Rossetti depicts his sister Christina in The Girlhood of Mary Virgin | |
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| 1849 |
| | | Russian novelist Fyodor Dostoevsky undergoes a mock execution, after being sentenced to death for revolutionary activities against tsar Nicholas I | |
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| 1850 |
| | | Fyodor Dostoevsky begins four years of hard labour in Siberia for revolutionary activities | |
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| 1850 |
| | | Queen Victoria knights her favourite painter of animals, Edwin Landseer | |
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| c. 1850 |
| | | The Scottish missionary David Livingstone is profoundly shocked by what he sees of the slave trade at the heart of Africa | |
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| 1850 |
| | | The British government buys the Danish fortresses on the Gold Coast, including Christiansborg castle in Accra | |
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| 1850 |
| | | British foreign secretary Lord Palmerston sends a naval squadron to seize Greek ships in the Don Pacifico case | |
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| 1850 |
| | | The brothers James and John Harper launch in New York Harper's Monthly Magazine, still published today | |
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| 1850 |
| | | As many as 50,000 US pioneers travel west this year on the Oregon Trail | |
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