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| 1846 |
| | The US Congress establishes the Smithsonian Institution with a bequest to the nation by Englishman James Smithson | |
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| 1846 |
| | A dentist in Boston, William Morton, uses ether as an anaesthetic while surgeon John Collins Warren removes a tumour in a patient's neck | |
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| 1846 |
| | Landlords in Scotland begin to clear crofters from Highland estates so as to provide pasture for sheep | |
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| 1846 |
| | Members of the Donner Party, on the trail to California, survive by eating human flesh when trapped by snow in the mountains of the Sierra Nevada | |
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| 1846 |
| | The three Brontë sisters jointly publish a volume of their poems and sell just two copies | |
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| 1847 |
| | A new Factory Act is passed in Britain, limiting the working day of women and children to a maximum of ten hours | |
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| 1847 |
| | Scottish obstetrician James Simpson uses anaesthetic (ether, and later in the year choloroform) to ease difficulty in childbirth | |
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| 1847 |
| | English author William Makepeace Thackeray begins publication of his novel Vanity Fair in monthly parts (book form 1848) | |
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| 1847 |
| | Camillo Benso di Cavour founds a newspaper in north Italy and calls it Il Risorgimento ('The Resurgence') | |
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| 1847 |
| | At a congress in London Engels persuades a group of radical Germans to adopt the name Communist League | |
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