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| 331 BC |
| | | Alexander travels far into the desert, to a famous oracle of the sun god Amon (or Amon-Re) at Siwah, where the priest recognizes him as the son of the god | |
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| 331 BC |
| | | Moving northeast into Mesopotamia, Alexander again defeats Darius III (at Gaugamela), leaving Persia open to his advances | |
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| c. 330 BC |
| | | Aristotle tackles wide-ranging subjects on a systematic basis, leaving to his successors an encyclopedia of contemporary thought | |
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| 330 BC |
| | | As a conclusive end to the long rivalry between Greece and Persia, Alexander destroys the great palace of Xerxes at Persepolis | |
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| 330 BC |
| | | Alexander adopts the ceremonial dress and court rituals of of his new Persian empire | |
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| 330 BC |
| | | Alexander begins two years moving with his army through his vast new territories, establishing Greek settlements | |
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| 327 BC |
| | | Alexander marries Roxana after subduing the territories of her father, a Bactrian chief in the modern region of Aghanistan | |
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| 327 BC |
| | | Alexander takes a major new step, leaving Persian territory and moving through the mountain passes into India | |
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| 325 BC |
| | | In the Indian monsoon Alexander's Greek troops have finally had enough and threaten to mutiny unless he turns for home | |
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| 324 BC |
| | | Back in Persia, to emphasize that Greece and Persia are now one, Alexander marries eighty of his senior officers to Persian wives | |
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