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| 1745 |
| | | The principle of the Leyden jar is discovered by an amateur German physicist, Ewald Georg von Kleist, dean of the cathedral in Kamin | |
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| 1745 |
| | | Charles Edward Stuart lands at Eriskay in the Hebrides, launching the Forty-Five Rebellion | |
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| 1745 |
| | | Charles Edward Stuart gathers support for the Forty-Five Rebellion on his way south from the Hebrides and reaches Edinburgh | |
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| 1745 |
| | | Charles Edward Stuart marches as far south as Derby, but then turns back | |
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| 1745 |
| | | Frederick the Great's Prussian soldiers, advancing in shallow disciplined formation, outclass other armies of the time | |
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| 1745 |
| | | Frederick II's three victories in 1745 cause him to be known by his contemporaries as Frederick the Great | |
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| 1746 |
| | | Frederick the Great begins to build the summer palace of Sans Souci at Potsdam | |
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| 1746 |
| | | Charles Edward Stuart and his 5000 Scots are routed at Culloden, bringing the Forty-Five Rebellion to an abrupt end | |
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| 1746 |
| | | Tartan and Highland dress are banned by the British government, in a prohibition not lifted until 1782 | |
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| 1746 |
| | | An earthquake destroys much of Lima, and an ensuing tidal wave engulfs its port at Callao | |
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