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| 1549 |
| | The first version of the English prayer book, or Book of Common Prayer, is published with text by Thomas Cranmer | |
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| 1549 |
| | Joachim du Bellay publishes a manifesto for the group of new French poets who become known as the Pléiade | |
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| c. 1550 |
| | Africans, bought in the Portuguese trading posts of west Africa, are shipped across the Atlantic as slaves | |
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| 1550 |
| | The Mongols, increasingly dominated by their neighbours in Manchuria, submit to them and are accepted by the Manchus as vassals | |
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| c. 1550 |
| | The tinderbox provides a new way of making fire - with just flint, steel and tinder | |
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| c. 1550 |
| | Spanish galleons assemble each year at Portobelo to deliver European goods and to ship home the metals of Latin America | |
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| 1550 |
| | Pierre de Ronsard publishes the first four books of his Odes | |
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| 1553 |
| | Mary I succeeds to the English throne, and devotes her energies to the restoration of the Catholic faith | |
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| 1554 |
| | Mary I causes grave offence in England by her marriage to the Catholic heir to the king of Spain | |
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| 1554 |
| | Thomas Wyatt raises a Protestant rebellion in Yorkshire and marches south in a failed attempt to depose the English queen, Mary I | |
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